LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1209 4152 4093 1.0146 1.0207
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1209 1961 4093 0.4792 0.2607
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1209 1199 4093 0.2930 -0.0035
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1209 2264 4093 0.5533 0.3659
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1209 1502 4093 0.3671 0.1015
MCF7 BI-2536
0.04
uM
LJP6
 72
hr
 1209 1478 4093 0.3613 0.0933
MCF7 BMS345541
0.04
uM
LJP6
 72
hr
 1209 4237 4093 1.0353 1.0501
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1209 1200 4093 0.2932 -0.0033
MCF7 GDC-0980
0.04
uM
LJP5
 72
hr
 1209 1300 4093 0.3178 0.0316
MCF7 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1209 3941 4093 0.9629 0.9474
MCF7 SB590885
0.04
uM
LJP5
 72
hr
 1209 3687 4093 0.9008 0.8592
MCF7 PIK-93
0.04
uM
LJP5
 72
hr
 1209 4130 4093 1.0090 1.0128
MCF7 KIN001-043
0.04
uM
LJP6
 72
hr
 1209 3628 4093 0.8865 0.8389
MCF7 Alpelisib
0.04
uM
LJP5
 72
hr
 1209 3283 4093 0.8022 0.7192
MCF7 Luminespib
0.04
uM
LJP5
 72
hr
 1209 1245 4093 0.3042 0.0123
MCF7 A443654
0.04
uM
LJP6
 72
hr
 1209 1361 4093 0.3325 0.0525
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1209 3192 4093 0.7800 0.6876
MCF7 XMD11-85h
0.04
uM
LJP6
 72
hr
 1209 3440 4093 0.8406 0.7738
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1209 4320 4093 1.0555 1.0787
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1209 3748 4093 0.9157 0.8804
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1209 2751 4093 0.6721 0.5346
MCF7 XMD16-144
0.04
uM
LJP5
 72
hr
 1209 1543 4093 0.3772 0.1159
MCF7 Brivanib
0.04
uM
LJP5
 72
hr
 1209 4167 4093 1.0181 1.0257
MCF7 Buparlisib
0.04
uM
LJP5
 72
hr
 1209 2423 4093 0.5922 0.4211
MCF7 BX-912
0.04
uM
LJP5
 72
hr
 1209 3738 4093 0.9134 0.8771