LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 658 3389 3846 0.8812 0.8567
Hs 578T Sigma A6730
3.33
uM
LJP5
 72
hr
 658 3207 3846 0.8338 0.7995
Hs 578T Alvocidib
3.33
uM
LJP6
 72
hr
 658 419 3846 0.1090 -0.0749
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 658 341 3846 0.0888 -0.0993
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 658 446 3846 0.1161 -0.0664
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 658 2928 3846 0.7615 0.7122
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 658 272 3846 0.0707 -0.1211
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 658 848 3846 0.2205 0.0595
Hs 578T AZD8330
3.33
uM
LJP5
 72
hr
 658 1057 3846 0.2749 0.1252
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 658 1155 3846 0.3003 0.1558
Hs 578T BI-2536
3.33
uM
LJP6
 72
hr
 658 602 3846 0.1567 -0.0174
Hs 578T BMS345541
3.33
uM
LJP6
 72
hr
 658 2121 3846 0.5516 0.4590
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 658 532 3846 0.1385 -0.0394
Hs 578T GDC-0980
3.33
uM
LJP5
 72
hr
 658 1128 3846 0.2935 0.1476
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 658 3948 3846 1.0265 1.0320
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 658 3895 3846 1.0129 1.0155
Hs 578T PIK-93
3.33
uM
LJP5
 72
hr
 658 2580 3846 0.6709 0.6030
Hs 578T KIN001-043
3.33
uM
LJP6
 72
hr
 658 3480 3846 0.9049 0.8853
Hs 578T Alpelisib
3.33
uM
LJP5
 72
hr
 658 2892 3846 0.7519 0.7007
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 658 731 3846 0.1902 0.0229
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 658 294 3846 0.0764 -0.1142
Hs 578T OSI-027
3.33
uM
LJP6
 72
hr
 658 1638 3846 0.4259 0.3074
Hs 578T XMD11-85h
3.33
uM
LJP6
 72
hr
 658 3049 3846 0.7928 0.7501
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 658 576 3846 0.1499 -0.0256
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 658 460 3846 0.1196 -0.0622