LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Selumetinib
0.12
uM
LJP6
 72
hr
 658 2301 3846 0.5984 0.5154
Hs 578T Sirolimus
0.12
uM
LJP6
 72
hr
 658 2368 3846 0.6157 0.5363
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 658 4138 3846 1.0760 1.0917
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 658 3851 3846 1.0014 1.0016
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 658 3756 3846 0.9767 0.9718
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 658 3595 3846 0.9347 0.9212
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 658 1178 3846 0.3063 0.1631
Hs 578T Torin2
0.12
uM
LJP5
 72
hr
 658 779 3846 0.2025 0.0379
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 658 764 3846 0.1987 0.0333
Hs 578T Trametinib
0.12
uM
LJP5
 72
hr
 658 955 3846 0.2485 0.0933
Hs 578T TWS119
0.12
uM
LJP5
 72
hr
 658 3837 3846 0.9977 0.9973
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 658 4031 3846 1.0482 1.0581
Hs 578T Withaferin A
0.12
uM
LJP5
 72
hr
 658 4079 3846 1.0606 1.0731
Hs 578T Withaferin A
0.12
uM
LJP6
 72
hr
 658 3894 3846 1.0125 1.0151
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 658 1198 3846 0.3115 0.1693
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 658 431 3846 0.1122 -0.0711
Hs 578T XMD11-50
0.12
uM
LJP6
 72
hr
 658 3109 3846 0.8084 0.7689
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 658 3239 3846 0.8422 0.8096
Hs 578T YM 201636
0.12
uM
LJP5
 72
hr
 658 3853 3846 1.0019 1.0023
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 658 2500 3846 0.6500 0.5778
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 658 3611 3846 0.9390 0.9264
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 658 3572 3846 0.9288 0.9141
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 658 372 3846 0.0967 -0.0898
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 658 423 3846 0.1102 -0.0736
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 658 1037 3846 0.2697 0.1189