LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2519 | 5578 | 0.4515 | -0.0081 |
| SK-BR-3 | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 3118 | 5578 | 0.5590 | 0.1895 |
| SK-BR-3 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 2534 | 5578 | 0.4542 | -0.0031 |
| SK-BR-3 | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 4349 | 5578 | 0.7797 | 0.5951 |
| SK-BR-3 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1578 | 5578 | 0.2829 | -0.3181 |
| SK-BR-3 | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1530 | 5578 | 0.2743 | -0.3338 |
| SK-BR-3 | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1353 | 5578 | 0.2427 | -0.3920 |
| SK-BR-3 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1079 | 5578 | 0.1934 | -0.4825 |
| SK-BR-3 | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 4377 | 5578 | 0.7846 | 0.6041 |
| SK-BR-3 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1097 | 5578 | 0.1967 | -0.4765 |
| SK-BR-3 | PI103 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1624 | 5578 | 0.2912 | -0.3028 |
| SK-BR-3 | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2546 | 5578 | 0.4564 | 0.0008 |
| SK-BR-3 | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1254 | 5578 | 0.2248 | -0.4248 |
| SK-BR-3 | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1744 | 5578 | 0.3127 | -0.2633 |
| SK-BR-3 | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2277 | 5578 | 0.4083 | -0.0876 |
| SK-BR-3 | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1979 | 5578 | 0.3549 | -0.1858 |
| SK-BR-3 | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2998 | 5578 | 0.5375 | 0.1500 |
| SK-BR-3 | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 5506 | 5578 | 0.9871 | 0.9763 |
| SK-BR-3 | XL147 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 4152 | 5578 | 0.7443 | 0.5300 |
| SK-BR-3 | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 2760 | 5578 | 0.4947 | 0.0713 |
| SK-BR-3 | Selumetinib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 5264 | 5578 | 0.9437 | 0.8964 |
| SK-BR-3 | Sirolimus | 10.0 | uM | LJP6 | 72 | hr | 2543 | 3256 | 5578 | 0.5837 | 0.2349 |
| SK-BR-3 | Sorafenib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 2495 | 5578 | 0.4473 | -0.0159 |
| SK-BR-3 | SU11274 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2510 | 5578 | 0.4501 | -0.0108 |
| SK-BR-3 | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1643 | 5578 | 0.2945 | -0.2967 |