LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1308 | 5578 | 0.2346 | -0.4068 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1043 | 5578 | 0.1870 | -0.4944 |
| SK-BR-3 | MK2206 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3143 | 5578 | 0.5634 | 0.1975 |
| SK-BR-3 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1397 | 5578 | 0.2505 | -0.3776 |
| SK-BR-3 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 6066 | 5578 | 1.0874 | 1.1607 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4478 | 5578 | 0.8028 | 0.6376 |
| SK-BR-3 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4653 | 5578 | 0.8341 | 0.6951 |
| SK-BR-3 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2075 | 5578 | 0.3721 | -0.1541 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2919 | 5578 | 0.5233 | 0.1238 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4033 | 5578 | 0.7231 | 0.4910 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 3638 | 5578 | 0.6522 | 0.3607 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3929 | 5578 | 0.7043 | 0.4565 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 5616 | 5578 | 1.0068 | 1.0125 |
| SK-BR-3 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5495 | 5578 | 0.9851 | 0.9725 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1865 | 5578 | 0.3344 | -0.2233 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2286 | 5578 | 0.4099 | -0.0846 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1573 | 5578 | 0.2820 | -0.3197 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2136 | 5578 | 0.3829 | -0.1342 |
| SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5757 | 5578 | 1.0320 | 1.0589 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2108 | 5578 | 0.3779 | -0.1435 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1694 | 5578 | 0.3037 | -0.2798 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4164 | 5578 | 0.7464 | 0.5339 |
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2425 | 5578 | 0.4348 | -0.0388 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1409 | 5578 | 0.2527 | -0.3736 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2231 | 5578 | 0.4000 | -0.1027 |