LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5319 | 5578 | 0.9535 | 0.9146 |
| SK-BR-3 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2595 | 5578 | 0.4652 | 0.0171 |
| SK-BR-3 | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4082 | 5578 | 0.7317 | 0.5069 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2165 | 5578 | 0.3882 | -0.1245 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2065 | 5578 | 0.3702 | -0.1575 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4854 | 5578 | 0.8702 | 0.7615 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3471 | 5578 | 0.6223 | 0.3058 |
| SK-BR-3 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5413 | 5578 | 0.9703 | 0.9454 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1501 | 5578 | 0.2691 | -0.3435 |
| SK-BR-3 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4271 | 5578 | 0.7656 | 0.5692 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1972 | 5578 | 0.3536 | -0.1881 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4512 | 5578 | 0.8089 | 0.6487 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4274 | 5578 | 0.7663 | 0.5704 |
| SK-BR-3 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5369 | 5578 | 0.9625 | 0.9310 |
| SK-BR-3 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4637 | 5578 | 0.8313 | 0.6899 |
| SK-BR-3 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4126 | 5578 | 0.7396 | 0.5214 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2186 | 5578 | 0.3919 | -0.1178 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5986 | 5578 | 1.0731 | 1.1343 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5619 | 5578 | 1.0072 | 1.0133 |
| SK-BR-3 | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5254 | 5578 | 0.9419 | 0.8933 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1784 | 5578 | 0.3199 | -0.2501 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1404 | 5578 | 0.2517 | -0.3753 |
| SK-BR-3 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3718 | 5578 | 0.6665 | 0.3870 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1519 | 5578 | 0.2724 | -0.3374 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6352 | 5578 | 1.1387 | 1.2550 |