LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5231 | 5578 | 0.9377 | 0.8856 |
| SK-BR-3 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5232 | 5578 | 0.9379 | 0.8859 |
| SK-BR-3 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2042 | 5578 | 0.3661 | -0.1651 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5416 | 5578 | 0.9709 | 0.9465 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4243 | 5578 | 0.7606 | 0.5599 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5303 | 5578 | 0.9506 | 0.9092 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5238 | 5578 | 0.9390 | 0.8879 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5533 | 5578 | 0.9918 | 0.9850 |
| SK-BR-3 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5866 | 5578 | 1.0516 | 1.0948 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1687 | 5578 | 0.3025 | -0.2821 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 3422 | 5578 | 0.6135 | 0.2896 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1575 | 5578 | 0.2824 | -0.3190 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4812 | 5578 | 0.8626 | 0.7474 |
| SK-BR-3 | PHA-665752 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5942 | 5578 | 1.0652 | 1.1199 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2348 | 5578 | 0.4210 | -0.0642 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3290 | 5578 | 0.5898 | 0.2461 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6025 | 5578 | 1.0801 | 1.1472 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2880 | 5578 | 0.5163 | 0.1110 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2650 | 5578 | 0.4751 | 0.0353 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2336 | 5578 | 0.4189 | -0.0681 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2200 | 5578 | 0.3945 | -0.1129 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5645 | 5578 | 1.0120 | 1.0221 |
| SK-BR-3 | Ruxolitinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5483 | 5578 | 0.9829 | 0.9685 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5762 | 5578 | 1.0329 | 1.0605 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5274 | 5578 | 0.9454 | 0.8996 |