LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Crizotinib
0.04
uM
LJP5
 72
hr
 765 3186 3124 1.0197 1.0260
Hs 578T Dasatinib
0.04
uM
LJP6
 72
hr
 765 1008 3124 0.3226 0.1030
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 765 2478 3124 0.7932 0.7261
Hs 578T Erlotinib
0.04
uM
LJP5
 72
hr
 765 3116 3124 0.9973 0.9964
Hs 578T Foretinib
0.04
uM
LJP5
 72
hr
 765 2808 3124 0.8989 0.8661
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 765 2933 3124 0.9387 0.9188
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 765 3079 3124 0.9855 0.9808
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 765 2849 3124 0.9120 0.8835
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 765 2937 3124 0.9400 0.9205
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3124 0.3590 0.1511
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 765 1146 3124 0.3670 0.1617
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 765 440 3124 0.1409 -0.1376
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 765 3082 3124 0.9864 0.9820
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 765 3790 3124 1.2132 1.2823
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 765 3167 3124 1.0136 1.0180
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 765 3014 3124 0.9646 0.9532
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 765 690 3124 0.2208 -0.0318
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 765 3051 3124 0.9765 0.9688
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 765 3471 3124 1.1111 1.1471
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 765 2191 3124 0.7012 0.6044
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 765 1365 3124 0.4371 0.2546
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 765 3178 3124 1.0171 1.0227
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 765 2650 3124 0.8481 0.7989
Hs 578T Geldanamycin
0.04
uM
LJP6
 72
hr
 765 2604 3124 0.8334 0.7794
Hs 578T Geldanamycin
0.04
uM
LJP5
 72
hr
 765 2541 3124 0.8132 0.7527