LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 765 628 3124 0.2010 -0.0581
Hs 578T Pelitinib
10.0
uM
LJP5
 72
hr
 765 628 3124 0.2011 -0.0579
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 1694 630 11155 0.0565 -0.1125
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1334 631 3970 0.1590 -0.2668
Hs 578T HG-5-113-01
10.0
uM
LJP5
 72
hr
 765 631 3124 0.2022 -0.0565
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 765 632 3124 0.2025 -0.0561
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 72
hr
 1311 641 5013 0.1279 -0.1811
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 72
hr
 1311 642 5013 0.1281 -0.1809
Hs 578T PD0325901
10.0
uM
LJP5
 72
hr
 765 643 3124 0.2060 -0.0514
BT-20 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1334 645 3970 0.1626 -0.2614
Hs 578T R406
10.0
uM
LJP6
 72
hr
 765 646 3124 0.2070 -0.0502
Hs 578T NVP-AEW541
10.0
uM
LJP5
 72
hr
 765 647 3124 0.2071 -0.0500
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1334 647 3970 0.1629 -0.2609
BT-20 GW843682X
10.0
uM
LJP6
 72
hr
 1334 648 3970 0.1633 -0.2604
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 765 649 3124 0.2077 -0.0492
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 72
hr
 1311 652 5013 0.1301 -0.1781
Hs 578T WYE-125132
10.0
uM
LJP6
 72
hr
 765 658 3124 0.2108 -0.0451
MCF7 CGP60474
0.12
uM
LJP6
 72
hr
 1389 659 5667 0.1164 -0.1705
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 765 661 3124 0.2117 -0.0440
Hs 578T Crizotinib
10.0
uM
LJP5
 72
hr
 765 662 3124 0.2119 -0.0437
Hs 578T Nilotinib
10.0
uM
LJP5
 72
hr
 765 662 3124 0.2121 -0.0434
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 765 664 3124 0.2127 -0.0425
MCF7 PF431396
10.0
uM
LJP5
 72
hr
 1389 665 5667 0.1173 -0.1692
BT-20 Torin2
10.0
uM
LJP5
 72
hr
 1334 667 3970 0.1681 -0.2530
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 765 669 3124 0.2141 -0.0407