LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1097 | 5578 | 0.1967 | -0.4765 |
| SK-BR-3 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1112 | 5578 | 0.1993 | -0.4716 |
| SK-BR-3 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1120 | 5578 | 0.2008 | -0.4690 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1140 | 5578 | 0.2044 | -0.4623 |
| SK-BR-3 | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1147 | 5578 | 0.2056 | -0.4601 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1155 | 5578 | 0.2071 | -0.4573 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1157 | 5578 | 0.2074 | -0.4568 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1167 | 5578 | 0.2093 | -0.4534 |
| SK-BR-3 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1181 | 5578 | 0.2117 | -0.4489 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1182 | 5578 | 0.2119 | -0.4485 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1188 | 5578 | 0.2131 | -0.4464 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1190 | 5578 | 0.2134 | -0.4457 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1190 | 5578 | 0.2134 | -0.4457 |
| SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1198 | 5578 | 0.2148 | -0.4433 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1204 | 5578 | 0.2159 | -0.4411 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1222 | 5578 | 0.2191 | -0.4353 |
| SK-BR-3 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1222 | 5578 | 0.2191 | -0.4353 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1225 | 5578 | 0.2196 | -0.4344 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1226 | 5578 | 0.2198 | -0.4340 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1251 | 5578 | 0.2244 | -0.4256 |
| SK-BR-3 | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1254 | 5578 | 0.2248 | -0.4248 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1260 | 5578 | 0.2259 | -0.4229 |
| BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 232 | 3970 | 0.0586 | -0.4180 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1281 | 5578 | 0.2297 | -0.4157 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1289 | 5578 | 0.2312 | -0.4131 |