LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 781 | 3970 | 0.1969 | -0.2098 |
| BT-20 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 782 | 3970 | 0.1969 | -0.2097 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1909 | 5578 | 0.3423 | -0.2088 |
| BT-20 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 784 | 3970 | 0.1976 | -0.2086 |
| MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 503 | 5667 | 0.0887 | -0.2071 |
| SK-BR-3 | WYE-125132 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1916 | 5578 | 0.3436 | -0.2065 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1917 | 5578 | 0.3437 | -0.2063 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 509 | 5667 | 0.0898 | -0.2057 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1334 | 796 | 3970 | 0.2005 | -0.2042 |
| SK-BR-3 | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1926 | 5578 | 0.3453 | -0.2033 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1311 | 560 | 5013 | 0.1118 | -0.2030 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 522 | 5667 | 0.0922 | -0.2026 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1929 | 5578 | 0.3458 | -0.2024 |
| BT-20 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 801 | 3970 | 0.2019 | -0.2022 |
| BT-20 | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 803 | 3970 | 0.2023 | -0.2016 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 765 | 292 | 3124 | 0.0935 | -0.2005 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1935 | 5578 | 0.3469 | -0.2005 |
| SK-BR-3 | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1935 | 5578 | 0.3469 | -0.2004 |
| MCF7 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 532 | 5667 | 0.0939 | -0.2003 |
| SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1938 | 5578 | 0.3474 | -0.1995 |
| MCF7 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 536 | 5667 | 0.0947 | -0.1993 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1938 | 5578 | 0.3475 | -0.1993 |
| BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 809 | 3970 | 0.2039 | -0.1992 |
| BT-20 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 812 | 3970 | 0.2045 | -0.1983 |
| BT-20 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1334 | 812 | 3970 | 0.2046 | -0.1981 |