LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1311 | 677 | 5013 | 0.1351 | -0.1714 |
| Hs 578T | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 765 | 422 | 3124 | 0.1352 | -0.1453 |
| MDA-MB-231 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1311 | 680 | 5013 | 0.1357 | -0.1706 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 680 | 5013 | 0.1357 | -0.1706 |
| Hs 578T | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 765 | 424 | 3124 | 0.1359 | -0.1443 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 771 | 5667 | 0.1360 | -0.1445 |
| MCF 10A | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1519 | 11155 | 0.1362 | -0.0185 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 765 | 428 | 3124 | 0.1370 | -0.1429 |
| SK-BR-3 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 768 | 5578 | 0.1378 | -0.5847 |
| Hs 578T | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 765 | 431 | 3124 | 0.1379 | -0.1416 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 782 | 5667 | 0.1380 | -0.1419 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 782 | 5667 | 0.1381 | -0.1418 |
| Hs 578T | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 765 | 434 | 3124 | 0.1389 | -0.1403 |
| Hs 578T | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 765 | 434 | 3124 | 0.1391 | -0.1400 |
| MDA-MB-231 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1311 | 699 | 5013 | 0.1396 | -0.1653 |
| Hs 578T | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 765 | 440 | 3124 | 0.1409 | -0.1376 |
| MCF 10A | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 1580 | 11155 | 0.1416 | -0.0121 |
| Hs 578T | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 765 | 442 | 3124 | 0.1417 | -0.1366 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 803 | 5667 | 0.1418 | -0.1368 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 804 | 5667 | 0.1419 | -0.1367 |
| BT-20 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 1334 | 566 | 3970 | 0.1425 | -0.2916 |
| Hs 578T | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 765 | 445 | 3124 | 0.1426 | -0.1354 |
| MDA-MB-231 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1311 | 716 | 5013 | 0.1428 | -0.1609 |
| Hs 578T | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 765 | 446 | 3124 | 0.1430 | -0.1349 |
| Hs 578T | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 765 | 447 | 3124 | 0.1432 | -0.1347 |