LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1334 | 1612 | 3970 | 0.4061 | 0.1055 |
| BT-20 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 2662 | 3970 | 0.6705 | 0.5038 |
| BT-20 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3567 | 3970 | 0.8984 | 0.8469 |
| BT-20 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3868 | 3970 | 0.9743 | 0.9612 |
| BT-20 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1334 | 2899 | 3970 | 0.7301 | 0.5934 |
| BT-20 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3647 | 3970 | 0.9184 | 0.8771 |
| BT-20 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 4110 | 3970 | 1.0352 | 1.0530 |
| BT-20 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3110 | 3970 | 0.7833 | 0.6736 |
| BT-20 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 4145 | 3970 | 1.0439 | 1.0662 |
| BT-20 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3950 | 3970 | 0.9949 | 0.9923 |
| BT-20 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1334 | 608 | 3970 | 0.1532 | -0.2755 |
| BT-20 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1334 | 645 | 3970 | 0.1626 | -0.2614 |
| BT-20 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3232 | 3970 | 0.8141 | 0.7200 |
| BT-20 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 2789 | 3970 | 0.7025 | 0.5519 |
| BT-20 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 4129 | 3970 | 1.0398 | 1.0600 |
| BT-20 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3668 | 3970 | 0.9239 | 0.8854 |
| BT-20 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3738 | 3970 | 0.9414 | 0.9118 |
| BT-20 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 1371 | 3970 | 0.3453 | 0.0139 |
| BT-20 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3862 | 3970 | 0.9726 | 0.9587 |
| BT-20 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 2205 | 3970 | 0.5553 | 0.3301 |
| BT-20 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3477 | 3970 | 0.8758 | 0.8129 |
| BT-20 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3222 | 3970 | 0.8115 | 0.7160 |
| BT-20 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 4322 | 3970 | 1.0884 | 1.1332 |
| BT-20 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3994 | 3970 | 1.0059 | 1.0089 |
| BT-20 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3080 | 3970 | 0.7757 | 0.6622 |