LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10056-1 | Selumetinib | AZD6244; Array142886 | LSM-1056 |  | 10127622 |
| 10008-1 | Sorafenib | BAY-439006 | LSM-1008 |  | 216239 |
| 10232-1 | Dactolisib | BEZ235; NVP-BEZ235 | LSM-4255 |  | 11977753 |
| 10151-1 | Nintedanib | BIBF-1120; Vargatef | LSM-1152 |  | 56965894 |
| 10133-1 | Afatinib | BIBW-2992 | LSM-43226 |  | 57519523 |
| 10147-1 | Buparlisib | BKM120; NVP-BKM120 | LSM-1148 |  | 16654980 |
| 10020-1 | Dasatinib | BMS-354825; Sprycel | LSM-1020 |  | 3062316 |
| 10132-1 | SNS-032 | BMS-387032 | LSM-1132 |  | 3025986 |
| 10177-1 | Brivanib | BMS-540215 | LSM-1178 |  | 11451527 |
| 10233-1 | Alpelisib | BYL719 | LSM-4256 |  | 56649450 |
| 10120-1 | Canertinib | CI-1033; PD-183805 | LSM-1120 |  | 156414 |
| 10048-1 | PD184352 | CI-1040 | LSM-1048 |  | 6918454 |
| 10479-1 | Mitoxantrone | CL 232325; CL-232325; DHAQ; Novantron; Novantrone | LSM-2481 |  | 4212 |
| 10180-1 | CHIR-99021 | CT99021; KIN001-157 | LSM-1181 |  | 9956119 |
| 10140-1 | Momelotinib | CYT387 | LSM-1141 |  | 25062766 |
| 10115-1 | LDN-193189 | DM 3189 | LSM-1115 |  | 25195294 |
| 10159-1 | Pelitinib | EKB-569 | LSM-1160 |  | 216467 |
| 10011-1 | Alvocidib | Flavopiridol; HMR-1275; L868275 | LSM-1011 |  | 5287969 |
| 10023-1 | Imatinib | Gleevec; Glivec; CGP-57148B; STI-571 | LSM-1023 |  | 5291 |
| 10142-1 | Trametinib | GSK-1120212; GSK1120212; GSK1120212B; JTP-74057 | LSM-1143 |  | 11707110 |
| 10146-1 | Omipalisib | GSK2126458; GSK2126458A | LSM-1147 |  | 25167777 |
| 10051-1 | Lapatinib | GW-572016; Tykerb | LSM-1051 |  | 208908 |
| 10014-1 | GW843682X | GW843682 | LSM-1014 |  | 9826308 |
| 10018-1 | Neratinib | HKI-272 | LSM-42778 |  | 53398697 |
| 10035-1 | Sigma A6730 | KIN001-102; AKT inhibitor VIII; Akt1/2 kinase inhibitor | LSM-1035 |  | 10196499 |