LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1228 | 3694 | 0.3326 | -0.1119 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 2085 | 3694 | 0.5646 | 0.2746 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1476 | 861 | 3694 | 0.2332 | -0.2775 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 788 | 3694 | 0.2133 | -0.3106 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 807 | 3694 | 0.2186 | -0.3017 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1198 | 3694 | 0.3244 | -0.1256 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1002 | 3694 | 0.2713 | -0.2139 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1074 | 3694 | 0.2907 | -0.1816 |
| SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 3188 | 3694 | 0.8631 | 0.7719 |
| SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1365 | 3694 | 0.3696 | -0.0502 |
| SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1415 | 3694 | 0.3832 | -0.0275 |
| SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1195 | 3694 | 0.3237 | -0.1268 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 823 | 3694 | 0.2230 | -0.2945 |
| SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1434 | 3694 | 0.3882 | -0.0193 |
| SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1451 | 3694 | 0.3930 | -0.0113 |
| SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1132 | 3694 | 0.3066 | -0.1552 |
| SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1681 | 3694 | 0.4552 | 0.0924 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1722 | 3694 | 0.4663 | 0.1109 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1181 | 3694 | 0.3199 | -0.1331 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1525 | 3694 | 0.4130 | 0.0221 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 988 | 3694 | 0.2675 | -0.2204 |
| SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 1650 | 3694 | 0.4467 | 0.0781 |
| SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1476 | 2332 | 3694 | 0.6315 | 0.3860 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1476 | 809 | 3694 | 0.2192 | -0.3008 |
| SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1476 | 1188 | 3694 | 0.3217 | -0.1301 |