LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 929 1764 3228 0.5466 0.3633
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 929 1262 3228 0.3911 0.1449
MCF7 AZD7762
10.0
uM
LJP6
 72
hr
 1235 765 4156 0.1842 -0.1608
SK-BR-3 AZD7762
10.0
uM
LJP6
 72
hr
 1476 1002 3694 0.2713 -0.2139
SK-BR-3 AZD7762
3.33
uM
LJP6
 72
hr
 1476 1004 3694 0.2720 -0.2129
SK-BR-3 AZD7762
0.12
uM
LJP6
 72
hr
 1476 1351 3694 0.3659 -0.0564
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 1476 1505 3694 0.4074 0.0128
SK-BR-3 AZD7762
1.11
uM
LJP6
 72
hr
 1476 1052 3694 0.2850 -0.1912
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 513 6866 10401 0.6602 0.6425
MCF7 AZD7762
1.11
uM
LJP6
 72
hr
 1235 1310 4156 0.3153 0.0257
Hs 578T AZD7762
10.0
uM
LJP6
 72
hr
 929 715 3228 0.2216 -0.0931
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 513 3341 10401 0.3213 0.2860
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 513 1722 10401 0.1656 0.1223
MDA-MB-231 AZD8055
0.37
uM
LJP6
 72
hr
 868 1365 3486 0.3915 0.1898
MDA-MB-231 AZD8055
0.12
uM
LJP6
 72
hr
 868 1409 3486 0.4043 0.2068
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 929 1254 3228 0.3887 0.1416
BT-20 AZD8055
0.12
uM
LJP6
 72
hr
 1657 2341 5505 0.4253 0.1777
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10401 0.2407 0.2013
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 513 927 10401 0.0892 0.0419
BT-20 AZD8055
0.37
uM
LJP6
 72
hr
 1657 1984 5505 0.3604 0.0848
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 929 1276 3228 0.3955 0.1511
MDA-MB-231 AZD8055
10.0
uM
LJP6
 72
hr
 868 980 3486 0.2812 0.0429
MCF 10A AZD8055
10.0
uM
LJP6
 72
hr
 513 840 10401 0.0808 0.0330
MDA-MB-231 AZD8055
3.33
uM
LJP6
 72
hr
 868 1260 3486 0.3616 0.1499
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 513 1215 10401 0.1168 0.0710