LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1556 | 5505 | 0.2827 | -0.0263 |
| BT-20 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5328 | 5505 | 0.9679 | 0.9540 |
| SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2344 | 3694 | 0.6346 | 0.3913 |
| MCF 10A | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 513 | 8086 | 10401 | 0.7775 | 0.7659 |
| SK-BR-3 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3495 | 3694 | 0.9461 | 0.9102 |
| BT-20 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 2461 | 5505 | 0.4471 | 0.2088 |
| Hs 578T | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 929 | 2916 | 3228 | 0.9035 | 0.8645 |
| Hs 578T | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 929 | 2784 | 3228 | 0.8626 | 0.8071 |
| MDA-MB-231 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 868 | 1260 | 3486 | 0.3615 | 0.1498 |
| MCF 10A | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 513 | 9739 | 10401 | 0.9364 | 0.9331 |
| MCF 10A | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 513 | 6398 | 10401 | 0.6152 | 0.5952 |
| MDA-MB-231 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3178 | 3486 | 0.9115 | 0.8822 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2813 | 4156 | 0.6770 | 0.5404 |
| Hs 578T | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 929 | 1568 | 3228 | 0.4857 | 0.2779 |
| Hs 578T | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 929 | 2562 | 3228 | 0.7938 | 0.7104 |
| MDA-MB-231 | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 868 | 3027 | 3486 | 0.8682 | 0.8245 |
| MCF 10A | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 513 | 7846 | 10401 | 0.7543 | 0.7416 |
| BT-20 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 3514 | 5505 | 0.6383 | 0.4824 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4006 | 4156 | 0.9640 | 0.9487 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4799 | 4156 | 1.1547 | 1.2202 |
| MCF7 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1087 | 4156 | 0.2615 | -0.0508 |
| MCF7 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3850 | 4156 | 0.9264 | 0.8953 |
| Hs 578T | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3064 | 3228 | 0.9492 | 0.9286 |
| MDA-MB-231 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 868 | 1993 | 3486 | 0.5718 | 0.4299 |
| MDA-MB-231 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2355 | 3486 | 0.6757 | 0.5681 |