LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 513 | 387 | 10401 | 0.0372 | -0.0128 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 513 | 389 | 10401 | 0.0374 | -0.0125 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 513 | 393 | 10401 | 0.0378 | -0.0122 |
| MCF 10A | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 513 | 397 | 10401 | 0.0382 | -0.0117 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 513 | 398 | 10401 | 0.0383 | -0.0117 |
| MCF 10A | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 513 | 403 | 10401 | 0.0387 | -0.0112 |
| MCF 10A | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 513 | 402 | 10401 | 0.0387 | -0.0113 |
| MCF 10A | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 513 | 407 | 10401 | 0.0391 | -0.0108 |
| MCF 10A | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 513 | 407 | 10401 | 0.0391 | -0.0108 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 410 | 10401 | 0.0395 | -0.0104 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 72 | hr | 513 | 415 | 10401 | 0.0400 | -0.0099 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 513 | 419 | 10401 | 0.0403 | -0.0095 |
| MCF 10A | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 513 | 427 | 10401 | 0.0411 | -0.0087 |
| MCF 10A | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 513 | 431 | 10401 | 0.0414 | -0.0083 |
| MCF 10A | A443654 | 1.11 | uM | LJP6 | 72 | hr | 513 | 445 | 10401 | 0.0428 | -0.0069 |
| MCF 10A | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 513 | 446 | 10401 | 0.0429 | -0.0067 |
| MCF 10A | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 513 | 447 | 10401 | 0.0430 | -0.0067 |
| MCF 10A | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 513 | 450 | 10401 | 0.0433 | -0.0064 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 513 | 452 | 10401 | 0.0435 | -0.0062 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 513 | 458 | 10401 | 0.0441 | -0.0056 |
| MCF 10A | GSK1059615 | 3.33 | uM | LJP6 | 72 | hr | 513 | 459 | 10401 | 0.0441 | -0.0055 |
| MCF 10A | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 463 | 10401 | 0.0445 | -0.0051 |
| MCF 10A | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 513 | 464 | 10401 | 0.0446 | -0.0050 |
| MCF 10A | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 513 | 465 | 10401 | 0.0447 | -0.0049 |
| MCF 10A | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 513 | 467 | 10401 | 0.0450 | -0.0046 |