LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1463 | 4156 | 0.3521 | 0.0780 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3178 | 4156 | 0.7648 | 0.6653 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1206 | 4156 | 0.2903 | -0.0098 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1021 | 4156 | 0.2457 | -0.0734 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1933 | 4156 | 0.4651 | 0.2389 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1709 | 4156 | 0.4113 | 0.1623 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1593 | 4156 | 0.3833 | 0.1224 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4840 | 4156 | 1.1647 | 1.2344 |
| MCF7 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2897 | 4156 | 0.6970 | 0.5689 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1938 | 4156 | 0.4663 | 0.2406 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1215 | 4156 | 0.2923 | -0.0070 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1674 | 4156 | 0.4028 | 0.1502 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 986 | 4156 | 0.2372 | -0.0854 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3763 | 4156 | 0.9055 | 0.8655 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1143 | 4156 | 0.2751 | -0.0315 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1148 | 4156 | 0.2762 | -0.0299 |
| MCF7 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3327 | 4156 | 0.8007 | 0.7163 |
| MCF7 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1527 | 4156 | 0.3676 | 0.1001 |
| MCF7 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 979 | 4156 | 0.2356 | -0.0877 |
| MCF7 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1664 | 4156 | 0.4005 | 0.1469 |
| MCF7 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1503 | 4156 | 0.3618 | 0.0919 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3101 | 4156 | 0.7461 | 0.6387 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4398 | 4156 | 1.0583 | 1.0829 |
| MCF7 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4700 | 4156 | 1.1309 | 1.1863 |
| MCF7 | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1502 | 4156 | 0.3614 | 0.0913 |