LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 WZ3105
0.12
uM
LJP5
 72
hr
 1657 2203 5505 0.4001 0.1417
BT-20 XMD11-50
0.12
uM
LJP6
 72
hr
 1657 4869 5505 0.8844 0.8345
BT-20 Y39983
0.12
uM
LJP6
 72
hr
 1657 5340 5505 0.9700 0.9571
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1657 5446 5505 0.9893 0.9847
BT-20 ZSTK474
0.12
uM
LJP6
 72
hr
 1657 4895 5505 0.8892 0.8415
BT-20 Afatinib
0.37
uM
LJP6
 72
hr
 1657 4690 5505 0.8520 0.7882
BT-20 Sigma A6730
0.37
uM
LJP5
 72
hr
 1657 5188 5505 0.9423 0.9174
BT-20 Alvocidib
0.37
uM
LJP6
 72
hr
 1657 1244 5505 0.2261 -0.1074
BT-20 AT-7519
0.37
uM
LJP6
 72
hr
 1657 1889 5505 0.3432 0.0603
BT-20 AZD 5438
0.37
uM
LJP6
 72
hr
 1657 2629 5505 0.4775 0.2524
BT-20 AZD-6482
0.37
uM
LJP5
 72
hr
 1657 4328 5505 0.7862 0.6940
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1657 4158 5505 0.7552 0.6498
BT-20 AZD8055
0.37
uM
LJP6
 72
hr
 1657 1984 5505 0.3604 0.0848
BT-20 AZD8330
0.37
uM
LJP5
 72
hr
 1657 4424 5505 0.8035 0.7189
BT-20 Barasertib
0.37
uM
LJP5
 72
hr
 1657 3393 5505 0.6164 0.4511
BT-20 BI-2536
0.37
uM
LJP6
 72
hr
 1657 1544 5505 0.2804 -0.0296
BT-20 BMS345541
0.37
uM
LJP6
 72
hr
 1657 5520 5505 1.0027 1.0038
BT-20 SNS-032
0.37
uM
LJP6
 72
hr
 1657 1197 5505 0.2175 -0.1196
BT-20 GDC-0980
0.37
uM
LJP5
 72
hr
 1657 1608 5505 0.2921 -0.0128
BT-20 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1657 5765 5505 1.0471 1.0674
BT-20 SB590885
0.37
uM
LJP5
 72
hr
 1657 5431 5505 0.9864 0.9806
BT-20 PIK-93
0.37
uM
LJP5
 72
hr
 1657 5886 5505 1.0692 1.0990
BT-20 KIN001-043
0.37
uM
LJP6
 72
hr
 1657 5458 5505 0.9914 0.9877
BT-20 Alpelisib
0.37
uM
LJP5
 72
hr
 1657 4172 5505 0.7578 0.6534
BT-20 Luminespib
0.37
uM
LJP5
 72
hr
 1657 1790 5505 0.3252 0.0345