LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5640 | 5505 | 1.0244 | 1.0349 |
BT-20 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4260 | 5505 | 0.7739 | 0.6765 |
BT-20 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5475 | 5505 | 0.9945 | 0.9921 |
BT-20 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 2120 | 5505 | 0.3851 | 0.1202 |
BT-20 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1774 | 5505 | 0.3222 | 0.0302 |
BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1142 | 5505 | 0.2075 | -0.1339 |
BT-20 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2599 | 5505 | 0.4722 | 0.2448 |
BT-20 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5117 | 5505 | 0.9295 | 0.8991 |
BT-20 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2994 | 5505 | 0.5438 | 0.3473 |
BT-20 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1422 | 5505 | 0.2583 | -0.0613 |
BT-20 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4261 | 5505 | 0.7741 | 0.6767 |
BT-20 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1958 | 5505 | 0.3556 | 0.0780 |
BT-20 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4970 | 5505 | 0.9028 | 0.8610 |
BT-20 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1133 | 5505 | 0.2059 | -0.1362 |
BT-20 | BX-912 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4240 | 5505 | 0.7702 | 0.6712 |
BT-20 | Canertinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4017 | 5505 | 0.7296 | 0.6131 |
BT-20 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1657 | 860 | 5505 | 0.1562 | -0.2073 |
BT-20 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1342 | 5505 | 0.2438 | -0.0821 |
BT-20 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 931 | 5505 | 0.1691 | -0.1889 |
BT-20 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5559 | 5505 | 1.0098 | 1.0140 |
BT-20 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4497 | 5505 | 0.8169 | 0.7380 |
BT-20 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5382 | 5505 | 0.9777 | 0.9680 |
BT-20 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3569 | 5505 | 0.6483 | 0.4968 |
BT-20 | Momelotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3604 | 5505 | 0.6547 | 0.5060 |
BT-20 | Dasatinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1332 | 5505 | 0.2420 | -0.0846 |