LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 SU11274
3.33
uM
LJP5
2
J08
72
hr
1401 3775 4223 0.8939 0.8412
SK-BR-3 SU11274
3.33
uM
LJP5
3
J08
72
hr
1401 4420 4223 1.0466 1.0698
SK-BR-3 Fedratinib
3.33
uM
LJP5
1
L02
72
hr
1401 2682 4223 0.6351 0.4538
SK-BR-3 Fedratinib
3.33
uM
LJP5
2
L02
72
hr
1401 2733 4223 0.6472 0.4719
SK-BR-3 Fedratinib
3.33
uM
LJP5
3
L02
72
hr
1401 3180 4223 0.7530 0.6303
SK-BR-3 TGX221
3.33
uM
LJP5
1
H20
72
hr
1401 3979 4223 0.9422 0.9135
SK-BR-3 TGX221
3.33
uM
LJP5
2
H20
72
hr
1401 4030 4223 0.9543 0.9316
SK-BR-3 TGX221
3.33
uM
LJP5
3
H20
72
hr
1401 4622 4223 1.0945 1.1414
SK-BR-3 Torin1
3.33
uM
LJP6
1
O14
72
hr
1401 1411 4223 0.3341 0.0034
SK-BR-3 Torin1
3.33
uM
LJP6
2
O14
72
hr
1401 1305 4223 0.3090 -0.0342
SK-BR-3 Torin1
3.33
uM
LJP6
3
O14
72
hr
1401 1485 4223 0.3516 0.0296
SK-BR-3 Torin2
3.33
uM
LJP5
1
I20
72
hr
1401 1020 4223 0.2415 -0.1352
SK-BR-3 Torin2
3.33
uM
LJP5
2
I20
72
hr
1401 1102 4223 0.2610 -0.1062
SK-BR-3 Torin2
3.33
uM
LJP5
3
I20
72
hr
1401 1070 4223 0.2534 -0.1175
SK-BR-3 Tozasertib
3.33
uM
LJP5
1
B14
72
hr
1401 1420 4223 0.3363 0.0065
SK-BR-3 Tozasertib
3.33
uM
LJP5
2
B14
72
hr
1401 1463 4223 0.3464 0.0218
SK-BR-3 Tozasertib
3.33
uM
LJP5
3
B14
72
hr
1401 1403 4223 0.3322 0.0005
SK-BR-3 Trametinib
3.33
uM
LJP5
1
P20
72
hr
1401 3143 4223 0.7442 0.6172
SK-BR-3 Trametinib
3.33
uM
LJP5
2
P20
72
hr
1401 3395 4223 0.8039 0.7065
SK-BR-3 Trametinib
3.33
uM
LJP5
3
P20
72
hr
1401 3924 4223 0.9292 0.8940
SK-BR-3 TWS119
3.33
uM
LJP5
1
M02
72
hr
1401 1740 4223 0.4120 0.1200
SK-BR-3 TWS119
3.33
uM
LJP5
2
M02
72
hr
1401 3792 4223 0.8979 0.8472
SK-BR-3 TWS119
3.33
uM
LJP5
3
M02
72
hr
1401 3555 4223 0.8418 0.7632
SK-BR-3 Vemurafenib
3.33
uM
LJP5
1
C14
72
hr
1401 4046 4223 0.9581 0.9372
SK-BR-3 Vemurafenib
3.33
uM
LJP5
2
C14
72
hr
1401 4302 4223 1.0187 1.0280