LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 868 1175 3486 0.3370 0.1172
MDA-MB-231 Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 868 1055 3486 0.3026 0.0714
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 868 3059 3486 0.8774 0.8368
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 2
F21
 72
hr
 868 3539 3486 1.0151 1.0201
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 3
F21
 72
hr
 868 3030 3486 0.8691 0.8257
MDA-MB-231 GW843682X
1.11
uM
LJP6
 1
B15
 72
hr
 868 1185 3486 0.3399 0.1210
MDA-MB-231 GW843682X
1.11
uM
LJP6
 2
B15
 72
hr
 868 1050 3486 0.3012 0.0695
MDA-MB-231 GW843682X
1.11
uM
LJP6
 3
B15
 72
hr
 868 923 3486 0.2647 0.0210
MDA-MB-231 HG-5-113-01
1.11
uM
LJP5
 1
B09
 72
hr
 868 1694 3486 0.4859 0.3154
MDA-MB-231 HG-5-113-01
1.11
uM
LJP5
 2
B09
 72
hr
 868 1649 3486 0.4730 0.2982
MDA-MB-231 HG-5-113-01
1.11
uM
LJP5
 3
B09
 72
hr
 868 1678 3486 0.4813 0.3093
MDA-MB-231 HG-5-88-01
1.11
uM
LJP6
 1
A21
 72
hr
 868 2163 3486 0.6204 0.4946
MDA-MB-231 HG-5-88-01
1.11
uM
LJP6
 2
A21
 72
hr
 868 2504 3486 0.7182 0.6248
MDA-MB-231 HG-5-88-01
1.11
uM
LJP6
 3
A21
 72
hr
 868 2490 3486 0.7142 0.6195
MDA-MB-231 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 868 3473 3486 0.9962 0.9949
MDA-MB-231 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 868 3870 3486 1.1100 1.1465
MDA-MB-231 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 868 3927 3486 1.1264 1.1683
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 868 1083 3486 0.3106 0.0821
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 868 1308 3486 0.3752 0.1680
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 868 1278 3486 0.3666 0.1566
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 1
B21
 72
hr
 868 2233 3486 0.6405 0.5213
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 2
B21
 72
hr
 868 1974 3486 0.5662 0.4224
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 3
B21
 72
hr
 868 1990 3486 0.5708 0.4285
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 868 3394 3486 0.9735 0.9647
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 868 3581 3486 1.0271 1.0361