LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 1 | K11 | 72 | hr | 1235 | 1910 | 4156 | 0.4596 | 0.2310 |
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 2 | K11 | 72 | hr | 1235 | 1717 | 4156 | 0.4131 | 0.1649 |
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 3 | K11 | 72 | hr | 1235 | 1753 | 4156 | 0.4218 | 0.1772 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 1235 | 4144 | 4156 | 0.9971 | 0.9958 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 2 | J05 | 72 | hr | 1235 | 4195 | 4156 | 1.0093 | 1.0133 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1235 | 5017 | 4156 | 1.2071 | 1.2947 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 1 | O17 | 72 | hr | 1235 | 3742 | 4156 | 0.9004 | 0.8582 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 2 | O17 | 72 | hr | 1235 | 4132 | 4156 | 0.9942 | 0.9917 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 3 | O17 | 72 | hr | 1235 | 3998 | 4156 | 0.9619 | 0.9459 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1235 | 4320 | 4156 | 1.0394 | 1.0561 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 2 | G11 | 72 | hr | 1235 | 4519 | 4156 | 1.0873 | 1.1242 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 3 | G11 | 72 | hr | 1235 | 4345 | 4156 | 1.0454 | 1.0647 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 1 | D11 | 72 | hr | 1235 | 2918 | 4156 | 0.7021 | 0.5761 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 2 | D11 | 72 | hr | 1235 | 3172 | 4156 | 0.7632 | 0.6631 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 3 | D11 | 72 | hr | 1235 | 2482 | 4156 | 0.5972 | 0.4268 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 1 | M11 | 72 | hr | 1235 | 3711 | 4156 | 0.8929 | 0.8476 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 2 | M11 | 72 | hr | 1235 | 2788 | 4156 | 0.6708 | 0.5316 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 3 | M11 | 72 | hr | 1235 | 3082 | 4156 | 0.7416 | 0.6322 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 1 | L17 | 72 | hr | 1235 | 2588 | 4156 | 0.6227 | 0.4631 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 2 | L17 | 72 | hr | 1235 | 2558 | 4156 | 0.6155 | 0.4528 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 3 | L17 | 72 | hr | 1235 | 2806 | 4156 | 0.6751 | 0.5377 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 1235 | 3391 | 4156 | 0.8159 | 0.7380 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 2 | B11 | 72 | hr | 1235 | 3779 | 4156 | 0.9093 | 0.8709 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 3 | B11 | 72 | hr | 1235 | 3513 | 4156 | 0.8453 | 0.7798 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 1 | J11 | 72 | hr | 1235 | 4847 | 4156 | 1.1662 | 1.2365 |