LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 3 | L05 | 72 | hr | 1235 | 1665 | 4156 | 0.4006 | 0.1471 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 1 | A11 | 72 | hr | 1235 | 1329 | 4156 | 0.3198 | 0.0321 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 2 | A11 | 72 | hr | 1235 | 1279 | 4156 | 0.3077 | 0.0149 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 3 | A11 | 72 | hr | 1235 | 1350 | 4156 | 0.3248 | 0.0392 |
| MCF7 | AZD8330 | 0.12 | uM | LJP5 | 1 | G23 | 72 | hr | 1235 | 1972 | 4156 | 0.4745 | 0.2522 |
| MCF7 | AZD8330 | 0.12 | uM | LJP5 | 2 | G23 | 72 | hr | 1235 | 1912 | 4156 | 0.4600 | 0.2317 |
| MCF7 | AZD8330 | 0.12 | uM | LJP5 | 3 | G23 | 72 | hr | 1235 | 2076 | 4156 | 0.4995 | 0.2878 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 1 | D11 | 72 | hr | 1235 | 1611 | 4156 | 0.3876 | 0.1286 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 2 | D11 | 72 | hr | 1235 | 1578 | 4156 | 0.3797 | 0.1173 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 3 | D11 | 72 | hr | 1235 | 1604 | 4156 | 0.3859 | 0.1262 |
| MCF7 | BI-2536 | 0.12 | uM | LJP6 | 1 | D17 | 72 | hr | 1235 | 1388 | 4156 | 0.3340 | 0.0523 |
| MCF7 | BI-2536 | 0.12 | uM | LJP6 | 2 | D17 | 72 | hr | 1235 | 1353 | 4156 | 0.3255 | 0.0403 |
| MCF7 | BI-2536 | 0.12 | uM | LJP6 | 3 | D17 | 72 | hr | 1235 | 1458 | 4156 | 0.3508 | 0.0762 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1235 | 4176 | 4156 | 1.0048 | 1.0068 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1235 | 4265 | 4156 | 1.0262 | 1.0373 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1235 | 4480 | 4156 | 1.0779 | 1.1109 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1235 | 456 | 4156 | 0.1097 | -0.2668 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 2 | H17 | 72 | hr | 1235 | 652 | 4156 | 0.1569 | -0.1997 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 3 | H17 | 72 | hr | 1235 | 790 | 4156 | 0.1901 | -0.1525 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1235 | 1146 | 4156 | 0.2757 | -0.0306 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1235 | 1202 | 4156 | 0.2892 | -0.0114 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1235 | 1142 | 4156 | 0.2748 | -0.0320 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1235 | 4065 | 4156 | 0.9781 | 0.9688 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 2 | E17 | 72 | hr | 1235 | 3504 | 4156 | 0.8431 | 0.7767 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1235 | 3963 | 4156 | 0.9535 | 0.9339 |