LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 1235 4695 4156 1.1296 1.1845
MCF7 YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 1235 4919 4156 1.1835 1.2612
MCF7 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 1235 3632 4156 0.8739 0.8205
MCF7 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 1235 3175 4156 0.7639 0.6641
MCF7 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 1235 3183 4156 0.7659 0.6668
MCF7 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1235 2862 4156 0.6886 0.5569
MCF7 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1235 2754 4156 0.6626 0.5199
MCF7 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1235 3056 4156 0.7353 0.6233
MCF7 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 1235 3183 4156 0.7659 0.6668
MCF7 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 1235 3222 4156 0.7752 0.6802
MCF7 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 1235 3240 4156 0.7796 0.6863
MCF7 Alvocidib
0.12
uM
LJP6
 1
A17
 72
hr
 1235 722 4156 0.1737 -0.1758
MCF7 Alvocidib
0.12
uM
LJP6
 2
A17
 72
hr
 1235 631 4156 0.1518 -0.2069
MCF7 Alvocidib
0.12
uM
LJP6
 3
A17
 72
hr
 1235 675 4156 0.1624 -0.1919
MCF7 AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 1235 1412 4156 0.3397 0.0605
MCF7 AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 1235 1407 4156 0.3385 0.0588
MCF7 AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 1235 1370 4156 0.3296 0.0461
MCF7 AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 1235 2096 4156 0.5043 0.2947
MCF7 AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 1235 2193 4156 0.5277 0.3279
MCF7 AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 1235 2116 4156 0.5091 0.3015
MCF7 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 1235 3646 4156 0.8773 0.8253
MCF7 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 1235 4063 4156 0.9776 0.9681
MCF7 AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 1235 3842 4156 0.9244 0.8924
MCF7 AZD7762
0.12
uM
LJP6
 1
L05
 72
hr
 1235 1766 4156 0.4249 0.1817
MCF7 AZD7762
0.12
uM
LJP6
 2
L05
 72
hr
 1235 1688 4156 0.4061 0.1550