LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 929 1762 3228 0.5458 0.3623
Hs 578T Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 929 1847 3228 0.5722 0.3992
Hs 578T Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 929 1779 3228 0.5511 0.3697
Hs 578T Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 929 1977 3228 0.6124 0.4558
Hs 578T Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 929 2358 3228 0.7305 0.6215
Hs 578T Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 929 2332 3228 0.7224 0.6102
Hs 578T Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 929 3814 3228 1.1815 1.2549
Hs 578T Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 929 3834 3228 1.1877 1.2636
Hs 578T Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 929 3789 3228 1.1738 1.2440
Hs 578T SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 929 3212 3228 0.9950 0.9930
Hs 578T SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 929 3138 3228 0.9721 0.9608
Hs 578T SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 929 3244 3228 1.0049 1.0069
Hs 578T Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 929 3089 3228 0.9569 0.9395
Hs 578T Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 929 3326 3228 1.0303 1.0426
Hs 578T Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 929 3256 3228 1.0087 1.0122
Hs 578T TGX221
0.12
uM
LJP5
 1
H23
 72
hr
 929 2512 3228 0.7783 0.6887
Hs 578T TGX221
0.12
uM
LJP5
 2
H23
 72
hr
 929 2953 3228 0.9148 0.8804
Hs 578T TGX221
0.12
uM
LJP5
 3
H23
 72
hr
 929 3008 3228 0.9318 0.9043
Hs 578T Torin1
0.12
uM
LJP6
 1
O17
 72
hr
 929 1308 3228 0.4052 0.1648
Hs 578T Torin1
0.12
uM
LJP6
 2
O17
 72
hr
 929 1464 3228 0.4535 0.2326
Hs 578T Torin1
0.12
uM
LJP6
 3
O17
 72
hr
 929 1402 3228 0.4343 0.2057
Hs 578T Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 929 1277 3228 0.3956 0.1513
Hs 578T Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 929 1302 3228 0.4033 0.1622
Hs 578T Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 929 1293 3228 0.4006 0.1582
Hs 578T Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 929 1294 3228 0.4009 0.1587