LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 929 3393 3228 1.0511 1.0717
Hs 578T SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 929 855 3228 0.2649 -0.0323
Hs 578T SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 929 807 3228 0.2500 -0.0532
Hs 578T SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 929 944 3228 0.2924 0.0064
Hs 578T GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 929 1752 3228 0.5427 0.3579
Hs 578T GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 929 1748 3228 0.5415 0.3562
Hs 578T GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 929 1848 3228 0.5725 0.3997
Hs 578T NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 929 3319 3228 1.0282 1.0396
Hs 578T NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 929 3389 3228 1.0499 1.0700
Hs 578T NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 929 3275 3228 1.0145 1.0204
Hs 578T SB590885
0.12
uM
LJP5
 1
L17
 72
hr
 929 3746 3228 1.1604 1.2253
Hs 578T SB590885
0.12
uM
LJP5
 2
L17
 72
hr
 929 3773 3228 1.1688 1.2371
Hs 578T SB590885
0.12
uM
LJP5
 3
L17
 72
hr
 929 3870 3228 1.1989 1.2792
Hs 578T PIK-93
0.12
uM
LJP5
 1
K17
 72
hr
 929 3357 3228 1.0399 1.0561
Hs 578T PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 929 3293 3228 1.0201 1.0282
Hs 578T PIK-93
0.12
uM
LJP5
 3
K17
 72
hr
 929 3334 3228 1.0328 1.0461
Hs 578T KIN001-043
0.12
uM
LJP6
 1
C11
 72
hr
 929 3353 3228 1.0387 1.0543
Hs 578T KIN001-043
0.12
uM
LJP6
 2
C11
 72
hr
 929 3371 3228 1.0443 1.0622
Hs 578T KIN001-043
0.12
uM
LJP6
 3
C11
 72
hr
 929 3337 3228 1.0337 1.0474
Hs 578T Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 929 2934 3228 0.9089 0.8721
Hs 578T Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 929 3015 3228 0.9340 0.9073
Hs 578T Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 929 3026 3228 0.9374 0.9121
Hs 578T Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 929 1285 3228 0.3981 0.1548
Hs 578T Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 929 1318 3228 0.4083 0.1691
Hs 578T Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 929 1375 3228 0.4260 0.1939