LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1476 | 1020 | 3694 | 0.2761 | -0.2060 |
| Hs 578T | Withaferin A | 10.0 | uM | LJP6 | 2 | G13 | 72 | hr | 929 | 456 | 3228 | 0.1413 | -0.2059 |
| Hs 578T | LDN-193189 | 10.0 | uM | LJP5 | 3 | G01 | 72 | hr | 929 | 456 | 3228 | 0.1413 | -0.2059 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 1235 | 636 | 4156 | 0.1530 | -0.2052 |
| MCF7 | TWS119 | 10.0 | uM | LJP5 | 2 | M01 | 72 | hr | 1235 | 636 | 4156 | 0.1530 | -0.2052 |
| Hs 578T | LDN-193189 | 10.0 | uM | LJP5 | 2 | G01 | 72 | hr | 929 | 458 | 3228 | 0.1419 | -0.2050 |
| MCF7 | Afatinib | 10.0 | uM | LJP6 | 3 | G19 | 72 | hr | 1235 | 637 | 4156 | 0.1533 | -0.2049 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 1 | I20 | 72 | hr | 1235 | 637 | 4156 | 0.1533 | -0.2049 |
| MDA-MB-231 | LDN-193189 | 10.0 | uM | LJP5 | 2 | G01 | 72 | hr | 868 | 332 | 3486 | 0.0952 | -0.2048 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1476 | 1023 | 3694 | 0.2769 | -0.2046 |
| BT-20 | Buparlisib | 10.0 | uM | LJP5 | 3 | H01 | 72 | hr | 1657 | 872 | 5505 | 0.1584 | -0.2042 |
| MCF7 | LDN-193189 | 10.0 | uM | LJP5 | 1 | G01 | 72 | hr | 1235 | 639 | 4156 | 0.1538 | -0.2042 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 1476 | 1025 | 3694 | 0.2775 | -0.2037 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 1235 | 642 | 4156 | 0.1545 | -0.2032 |
| MCF7 | MK2206 | 10.0 | uM | LJP6 | 1 | F01 | 72 | hr | 1235 | 642 | 4156 | 0.1545 | -0.2032 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 3 | G06 | 72 | hr | 1235 | 643 | 4156 | 0.1547 | -0.2028 |
| Hs 578T | Withaferin A | 10.0 | uM | LJP6 | 3 | G13 | 72 | hr | 929 | 463 | 3228 | 0.1434 | -0.2028 |
| BT-20 | Dasatinib | 10.0 | uM | LJP6 | 3 | I01 | 72 | hr | 1657 | 878 | 5505 | 0.1595 | -0.2026 |
| BT-20 | Torin1 | 10.0 | uM | LJP6 | 1 | O13 | 72 | hr | 1657 | 879 | 5505 | 0.1597 | -0.2024 |
| SK-BR-3 | NVP-TAE684 | 10.0 | uM | LJP6 | 2 | K13 | 72 | hr | 1476 | 1028 | 3694 | 0.2783 | -0.2024 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 2 | I20 | 72 | hr | 1235 | 645 | 4156 | 0.1552 | -0.2021 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP5 | 2 | F02 | 72 | hr | 1476 | 1029 | 3694 | 0.2786 | -0.2019 |
| MCF7 | Fedratinib | 10.0 | uM | LJP5 | 2 | L01 | 72 | hr | 1235 | 646 | 4156 | 0.1554 | -0.2018 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 929 | 467 | 3228 | 0.1447 | -0.2011 |
| BT-20 | Withaferin A | 10.0 | uM | LJP5 | 1 | G13 | 72 | hr | 1657 | 886 | 5505 | 0.1609 | -0.2006 |