LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Linifanib
1.11
uM
LJP6
2
J09
72
hr
1657 5758 5505 1.0458 1.0656
BT-20 Linifanib
1.11
uM
LJP6
3
J09
72
hr
1657 5764 5505 1.0469 1.0671
BT-20 Linsitinib
1.11
uM
LJP5
1
O21
72
hr
1657 4968 5505 0.9023 0.8603
BT-20 Linsitinib
1.11
uM
LJP5
2
O21
72
hr
1657 5101 5505 0.9265 0.8948
BT-20 Linsitinib
1.11
uM
LJP5
3
O21
72
hr
1657 4798 5505 0.8715 0.8161
BT-20 Mitoxantrone
1.11
uM
LJP5
1
C21
72
hr
1657 1456 5505 0.2645 -0.0524
BT-20 Mitoxantrone
1.11
uM
LJP5
2
C21
72
hr
1657 1398 5505 0.2539 -0.0675
BT-20 Mitoxantrone
1.11
uM
LJP5
3
C21
72
hr
1657 1627 5505 0.2955 -0.0080
BT-20 Mitoxantrone
1.11
uM
LJP6
1
C21
72
hr
1657 1370 5505 0.2488 -0.0748
BT-20 Mitoxantrone
1.11
uM
LJP6
2
C21
72
hr
1657 1493 5505 0.2712 -0.0428
BT-20 Mitoxantrone
1.11
uM
LJP6
3
C21
72
hr
1657 1550 5505 0.2815 -0.0280
BT-20 MK2206
1.11
uM
LJP6
1
F03
72
hr
1657 3468 5505 0.6299 0.4705
BT-20 MK2206
1.11
uM
LJP6
2
F03
72
hr
1657 3650 5505 0.6630 0.5178
BT-20 MK2206
1.11
uM
LJP6
3
F03
72
hr
1657 3498 5505 0.6354 0.4783
BT-20 Neratinib
1.11
uM
LJP5
1
A15
72
hr
1657 3874 5505 0.7036 0.5760
BT-20 Neratinib
1.11
uM
LJP5
2
A15
72
hr
1657 3988 5505 0.7243 0.6056
BT-20 Neratinib
1.11
uM
LJP5
3
A15
72
hr
1657 3521 5505 0.6395 0.4842
BT-20 Nilotinib
1.11
uM
LJP5
1
N15
72
hr
1657 5255 5505 0.9545 0.9349
BT-20 Nilotinib
1.11
uM
LJP5
2
N15
72
hr
1657 5514 5505 1.0015 1.0022
BT-20 Nilotinib
1.11
uM
LJP5
3
N15
72
hr
1657 5237 5505 0.9512 0.9302
BT-20 Nintedanib
1.11
uM
LJP6
1
H03
72
hr
1657 4669 5505 0.8480 0.7826
BT-20 Nintedanib
1.11
uM
LJP6
2
H03
72
hr
1657 5097 5505 0.9258 0.8938
BT-20 Nintedanib
1.11
uM
LJP6
3
H03
72
hr
1657 4664 5505 0.8471 0.7813
BT-20 NU7441
1.11
uM
LJP5
1
C09
72
hr
1657 5973 5505 1.0849 1.1215
BT-20 NU7441
1.11
uM
LJP5
2
C09
72
hr
1657 5268 5505 0.9568 0.9382