LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Buparlisib | 1.11 | uM | LJP5 | 2 | H03 | 72 | hr | 868 | 1832 | 3486 | 0.5255 | 0.3681 |
| MDA-MB-231 | Buparlisib | 1.11 | uM | LJP5 | 3 | H03 | 72 | hr | 868 | 1705 | 3486 | 0.4890 | 0.3196 |
| MDA-MB-231 | BX-912 | 1.11 | uM | LJP5 | 1 | L21 | 72 | hr | 868 | 1780 | 3486 | 0.5106 | 0.3483 |
| MDA-MB-231 | BX-912 | 1.11 | uM | LJP5 | 2 | L21 | 72 | hr | 868 | 2027 | 3486 | 0.5814 | 0.4426 |
| MDA-MB-231 | BX-912 | 1.11 | uM | LJP5 | 3 | L21 | 72 | hr | 868 | 1795 | 3486 | 0.5149 | 0.3540 |
| MDA-MB-231 | Canertinib | 1.11 | uM | LJP6 | 1 | H09 | 72 | hr | 868 | 2406 | 3486 | 0.6901 | 0.5874 |
| MDA-MB-231 | Canertinib | 1.11 | uM | LJP6 | 2 | H09 | 72 | hr | 868 | 3067 | 3486 | 0.8797 | 0.8398 |
| MDA-MB-231 | Canertinib | 1.11 | uM | LJP6 | 3 | H09 | 72 | hr | 868 | 2988 | 3486 | 0.8571 | 0.8097 |
| MDA-MB-231 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 868 | 846 | 3486 | 0.2427 | -0.0084 |
| MDA-MB-231 | Celastrol | 1.11 | uM | LJP6 | 2 | G09 | 72 | hr | 868 | 827 | 3486 | 0.2372 | -0.0157 |
| MDA-MB-231 | Celastrol | 1.11 | uM | LJP6 | 3 | G09 | 72 | hr | 868 | 958 | 3486 | 0.2748 | 0.0343 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP5 | 1 | F03 | 72 | hr | 868 | 652 | 3486 | 0.1870 | -0.0825 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP5 | 2 | F03 | 72 | hr | 868 | 613 | 3486 | 0.1758 | -0.0974 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP5 | 3 | F03 | 72 | hr | 868 | 723 | 3486 | 0.2074 | -0.0554 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 868 | 625 | 3486 | 0.1793 | -0.0929 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 2 | G03 | 72 | hr | 868 | 554 | 3486 | 0.1589 | -0.1200 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 868 | 685 | 3486 | 0.1965 | -0.0699 |
| MDA-MB-231 | CHIR-99021 | 1.11 | uM | LJP6 | 1 | P15 | 72 | hr | 868 | 2749 | 3486 | 0.7885 | 0.7184 |
| MDA-MB-231 | CHIR-99021 | 1.11 | uM | LJP6 | 2 | P15 | 72 | hr | 868 | 3073 | 3486 | 0.8814 | 0.8421 |
| MDA-MB-231 | CHIR-99021 | 1.11 | uM | LJP6 | 3 | P15 | 72 | hr | 868 | 2881 | 3486 | 0.8264 | 0.7688 |
| MDA-MB-231 | CP724714 | 1.11 | uM | LJP5 | 1 | A09 | 72 | hr | 868 | 2884 | 3486 | 0.8272 | 0.7699 |
| MDA-MB-231 | CP724714 | 1.11 | uM | LJP5 | 2 | A09 | 72 | hr | 868 | 2700 | 3486 | 0.7744 | 0.6997 |
| MDA-MB-231 | CP724714 | 1.11 | uM | LJP5 | 3 | A09 | 72 | hr | 868 | 2891 | 3486 | 0.8292 | 0.7726 |
| MDA-MB-231 | CP466722 | 1.11 | uM | LJP5 | 1 | I09 | 72 | hr | 868 | 3224 | 3486 | 0.9247 | 0.8998 |
| MDA-MB-231 | CP466722 | 1.11 | uM | LJP5 | 2 | I09 | 72 | hr | 868 | 3510 | 3486 | 1.0068 | 1.0090 |