LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 868 3210 3486 0.9207 0.8944
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 868 2620 3486 0.7515 0.6691
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 868 3286 3486 0.9425 0.9235
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 868 3377 3486 0.9686 0.9582
MDA-MB-231 XL147
0.12
uM
LJP5
 1
G11
 72
hr
 868 3546 3486 1.0171 1.0228
MDA-MB-231 XL147
0.12
uM
LJP5
 2
G11
 72
hr
 868 3726 3486 1.0687 1.0915
MDA-MB-231 XL147
0.12
uM
LJP5
 3
G11
 72
hr
 868 3743 3486 1.0736 1.0980
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 868 3254 3486 0.9333 0.9112
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 868 2696 3486 0.7733 0.6981
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 868 2594 3486 0.7440 0.6592
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 868 2589 3486 0.7426 0.6573
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 868 2495 3486 0.7156 0.6214
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 868 2475 3486 0.7099 0.6137
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 868 2625 3486 0.7529 0.6710
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 868 2749 3486 0.7885 0.7184
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 868 2811 3486 0.8063 0.7421
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 868 2935 3486 0.8418 0.7894
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 868 2849 3486 0.8172 0.7566
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 868 2612 3486 0.7492 0.6660
MDA-MB-231 SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 868 3344 3486 0.9592 0.9456
MDA-MB-231 SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 868 3881 3486 1.1132 1.1507
MDA-MB-231 SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 868 3459 3486 0.9921 0.9895
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 868 3123 3486 0.8958 0.8612
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 868 3777 3486 1.0834 1.1110
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 868 3331 3486 0.9554 0.9407