LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
0.04
uM
LJP6
 1
K12
 72
hr
 868 3986 3486 1.1433 1.1908
MDA-MB-231 Radicicol
0.04
uM
LJP6
 2
K12
 72
hr
 868 4308 3486 1.2357 1.3138
MDA-MB-231 Radicicol
0.04
uM
LJP6
 3
K12
 72
hr
 868 3652 3486 1.0475 1.0632
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 868 3512 3486 1.0073 1.0098
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 868 3827 3486 1.0977 1.1301
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 868 3570 3486 1.0240 1.0319
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 868 2976 3486 0.8536 0.8051
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 868 3366 3486 0.9655 0.9540
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 868 3140 3486 0.9006 0.8677
MDA-MB-231 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 868 3899 3486 1.1183 1.1576
MDA-MB-231 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 868 3809 3486 1.0925 1.1232
MDA-MB-231 XL147
0.04
uM
LJP5
 3
G12
 72
hr
 868 3540 3486 1.0154 1.0205
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 868 3495 3486 1.0025 1.0033
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 868 3283 3486 0.9417 0.9223
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 868 3237 3486 0.9285 0.9048
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 868 3141 3486 0.9009 0.8681
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 868 3298 3486 0.9460 0.9281
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 868 3274 3486 0.9391 0.9189
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 868 2979 3486 0.8545 0.8062
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 868 2884 3486 0.8272 0.7699
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 868 2743 3486 0.7868 0.7161
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 868 3644 3486 1.0452 1.0602
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 868 3388 3486 0.9718 0.9624
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 868 3311 3486 0.9497 0.9330
MDA-MB-231 SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 868 3716 3486 1.0659 1.0877