Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 1
IL18
 21.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 64.0 57
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 45.0 53
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 55.0 47
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 41.5 48
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 33.0 57
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 33.0 42
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 47.0 55
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 41.5 44
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 32.0 53
RA1869 IL-1 alpha 100
ng/mL
 1
IL18
 62.5 54
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 41.0 44
N2759 IL-1 alpha 100
ng/mL
 1
IL18
 45.0 46
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 38.0 59
RA1931 IL-1 alpha 100
ng/mL
 1
IL18
 44.0 47
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL18
 45.0 52
N2586 IL-1 alpha 100
ng/mL
 1
IL18
 47.0 45
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 35.5 46
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 17.0 47
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 21.0 67
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 15.0 58
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 12.0 34
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 21.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 17.5 52
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 17.0 52