Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL18
 18.5 60
N2586 IKK16 2.0
uM
 1
IL18
 17.0 57
RA1869 Tofacitinib 0.3
uM
 1
IL18
 19.5 42
RA1869 1
IL18
 27.5 48
N2759 Tofacitinib 0.3
uM
 1
IL18
 17.0 37
N2759 1
IL18
 23.0 54
RA1931 Tofacitinib 0.3
uM
 1
IL18
 19.0 57
RA1931 1
IL18
 20.0 32
N2586 Tofacitinib 0.3
uM
 1
IL18
 17.0 55
N2586 1
IL18
 21.0 45
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL18
 31.0 73
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL18
 25.5 60
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL18
 18.5 46
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL18
 20.5 64
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL18
 21.0 61
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL18
 21.0 54
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL18
 17.0 63
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL18
 19.0 45
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL18
 25.0 43
RA1869 TNF-a 100
ng/mL
 1
IL18
 31.5 46
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL18
 23.0 57
N2759 TNF-a 100
ng/mL
 1
IL18
 25.5 38
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL18
 22.0 51
RA1931 TNF-a 100
ng/mL
 1
IL18
 16.0 53
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL18
 23.0 53