Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL1-a
 484.0 64
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL1-a
 317.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL1-a
 288.0 71
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL1-a
 267.0 62
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL1-a
 295.0 65
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL1-a
 294.0 61
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL1-a
 278.0 57
RA2159 TNF-a 100
ng/mL
 4
IL1-a
 276.5 60
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL1-a
 357.0 45
N2645 TNF-a 100
ng/mL
 4
IL1-a
 228.0 31
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL1-a
 298.0 51
RA2708 TNF-a 100
ng/mL
 4
IL1-a
 367.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL1-a
 422.0 43
RA2159 IKK16 2.0
uM
 4
IL1-a
 337.5 50
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL1-a
 302.5 64
N2645 IKK16 2.0
uM
 4
IL1-a
 290.0 46
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL1-a
 291.0 49
RA2708 IKK16 2.0
uM
 4
IL1-a
 321.0 59
RA2159 Tofacitinib 0.3
uM
 4
IL1-a
 328.5 52
RA2159 4
IL1-a
 288.5 54
N2645 Tofacitinib 0.3
uM
 4
IL1-a
 370.0 55
N2645 4
IL1-a
 170.0 33
RA2708 Tofacitinib 0.3
uM
 4
IL1-a
 343.0 33
RA2708 4
IL1-a
 330.5 60
RA2159 4
IL1-a
 357.0 47