Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
4
G-CSF
75.0 69
RA2708 TNF-a 100
ng/mL
4
G-CSF
71.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
4
G-CSF
20.5 52
RA2159 IKK16 2.0
uM
4
G-CSF
22.0 70
N2645 5z-7-oxozeaenol 0.6
uM
4
G-CSF
23.5 70
N2645 IKK16 2.0
uM
4
G-CSF
19.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
4
G-CSF
17.5 62
RA2708 IKK16 2.0
uM
4
G-CSF
20.0 69
RA2159 Tofacitinib 0.3
uM
4
G-CSF
18.0 61
RA2159 4
G-CSF
20.0 70
N2645 Tofacitinib 0.3
uM
4
G-CSF
22.0 47
N2645 4
G-CSF
20.5 72
RA2708 Tofacitinib 0.3
uM
4
G-CSF
21.0 52
RA2708 4
G-CSF
21.0 49
RA2159 4
G-CSF
26.0 81
N2645 4
G-CSF
18.0 71
RA2708 4
G-CSF
21.0 75
RA2159 JNK-IN-8 3.0
uM
4
G-CSF
18.0 58
RA2159 PH-797804 0.6
uM
4
G-CSF
24.0 67
N2645 JNK-IN-8 3.0
uM
4
G-CSF
20.0 65
N2645 PH-797804 0.6
uM
4
G-CSF
23.0 60
RA2708 JNK-IN-8 3.0
uM
4
G-CSF
19.0 64
RA2708 PH-797804 0.6
uM
4
G-CSF
22.0 76
RA2159 Poly(I:C) 2
ug/mL
4
G-CSF
73.5 62
N2645 Poly(I:C) 2
ug/mL
4
G-CSF
95.0 61