Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Tofacitinib 0.3
uM
 2
G-CSF
 17.5 62
N2645 2
G-CSF
 18.0 72
RA2708 Tofacitinib 0.3
uM
 2
G-CSF
 15.0 71
RA2708 2
G-CSF
 17.0 78
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
G-CSF
 57.0 71
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
G-CSF
 55.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
G-CSF
 58.0 81
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
G-CSF
 58.0 77
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
G-CSF
 37.0 77
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
G-CSF
 62.0 63
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
G-CSF
 74.0 59
RA2159 TNF-a 100
ng/mL
 2
G-CSF
 67.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
G-CSF
 67.0 69
N2645 TNF-a 100
ng/mL
 2
G-CSF
 72.0 79
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
G-CSF
 60.5 72
RA2708 TNF-a 100
ng/mL
 2
G-CSF
 64.5 66
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 16.0 63
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 28.0 95
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 17.5 78
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 23.0 74
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 15.0 84
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 46.5 68
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 379.0 57
RA2159 IL-1 alpha 100
ng/mL
 2
G-CSF
 303.0 67
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
G-CSF
 52.0 69