Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 307.0 101
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 371.5 86
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 367.5 74
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 350.5 66
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 417.0 70
RA1869 TNF-a 100
ng/mL
 1
IL-1B
 428.5 78
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 422.0 71
N2759 TNF-a 100
ng/mL
 1
IL-1B
 465.0 56
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 440.5 58
RA1931 TNF-a 100
ng/mL
 1
IL-1B
 449.0 71
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 433.5 62
N2586 TNF-a 100
ng/mL
 1
IL-1B
 387.5 56
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 12.0 69
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 19.5 82
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 11.0 67
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 27.0 65
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 13.5 72
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 22.0 62
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 17.5 60
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 41.0 69
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 74.0 79
RA1869 IL-1 alpha 100
ng/mL
 1
IL-1B
 86.0 61
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 87.5 50
N2759 IL-1 alpha 100
ng/mL
 1
IL-1B
 93.0 54
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 76.0 46