Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 PH-797804 0.6
uM
 1
IL-1B
 12.0 75
RA1931 JNK-IN-8 3.0
uM
 1
IL-1B
 14.0 70
RA1931 PH-797804 0.6
uM
 1
IL-1B
 13.5 74
N2586 JNK-IN-8 3.0
uM
 1
IL-1B
 17.0 70
N2586 PH-797804 0.6
uM
 1
IL-1B
 13.0 84
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 12.0 83
RA1869 IKK16 2.0
uM
 1
IL-1B
 14.0 74
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 12.0 81
N2759 IKK16 2.0
uM
 1
IL-1B
 15.0 88
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 14.5 98
RA1931 IKK16 2.0
uM
 1
IL-1B
 9.0 101
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 16.0 82
N2586 IKK16 2.0
uM
 1
IL-1B
 14.0 83
RA1869 Tofacitinib 0.3
uM
 1
IL-1B
 13.5 60
RA1869 1
IL-1B
 16.0 67
N2759 Tofacitinib 0.3
uM
 1
IL-1B
 13.0 69
N2759 1
IL-1B
 13.0 83
RA1931 Tofacitinib 0.3
uM
 1
IL-1B
 18.0 74
RA1931 1
IL-1B
 13.0 50
N2586 Tofacitinib 0.3
uM
 1
IL-1B
 16.0 69
N2586 1
IL-1B
 13.0 58
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 439.0 69
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 370.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-1B
 372.0 91
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1B
 279.0 92