Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 IL-1 alpha 100
ng/mL
 1
IL-1B
 72.0 53
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1B
 96.0 55
N2586 IL-1 alpha 100
ng/mL
 1
IL-1B
 96.0 61
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 13.0 63
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.0 62
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 14.0 88
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 17.0 83
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.0 65
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.5 58
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 12.0 67
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 18.0 72
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 21.0 49
RA1869 Poly(I:C) 2
ug/mL
 1
IL-1B
 42.5 74
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 46.0 58
N2759 Poly(I:C) 2
ug/mL
 1
IL-1B
 65.0 53
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 59.0 59
RA1931 Poly(I:C) 2
ug/mL
 1
IL-1B
 14.5 48
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 87.0 59
N2586 Poly(I:C) 2
ug/mL
 1
IL-1B
 85.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 13.0 73
RA1869 IKK16 2.0
uM
 1
IL-1B
 13.0 68
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 11.0 73
N2759 IKK16 2.0
uM
 1
IL-1B
 12.0 75
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-1B
 14.0 61
RA1931 IKK16 2.0
uM
 1
IL-1B
 14.0 84