Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 4
MMP-1
 263.5 64
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MMP-1
 18300.0 63
RA2708 TNF-a 100
ng/mL
 4
MMP-1
 27473.5 72
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 114.0 80
RA2159 IKK16 2.0
uM
 4
MMP-1
 134.5 74
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 102.5 54
N2645 IKK16 2.0
uM
 4
MMP-1
 78.5 56
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 1539.0 84
RA2708 IKK16 2.0
uM
 4
MMP-1
 1222.0 71
RA2159 Tofacitinib 0.3
uM
 4
MMP-1
 99.0 66
RA2159 4
MMP-1
 125.0 50
N2645 Tofacitinib 0.3
uM
 4
MMP-1
 97.0 65
N2645 4
MMP-1
 80.0 73
RA2708 Tofacitinib 0.3
uM
 4
MMP-1
 1236.0 47
RA2708 4
MMP-1
 971.5 70
RA2159 4
MMP-1
 120.0 77
N2645 4
MMP-1
 66.0 58
RA2708 4
MMP-1
 2475.0 58
RA2159 JNK-IN-8 3.0
uM
 4
MMP-1
 148.0 63
RA2159 PH-797804 0.6
uM
 4
MMP-1
 156.0 83
N2645 JNK-IN-8 3.0
uM
 4
MMP-1
 73.0 63
N2645 PH-797804 0.6
uM
 4
MMP-1
 61.0 71
RA2708 JNK-IN-8 3.0
uM
 4
MMP-1
 1240.0 63
RA2708 PH-797804 0.6
uM
 4
MMP-1
 1213.0 48
RA2159 Poly(I:C) 2
ug/mL
 4
MMP-1
 237.5 58