Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 2
MMP-1
 133.0 66
N2645 Tofacitinib 0.3
uM
 2
MMP-1
 85.5 68
N2645 2
MMP-1
 69.0 55
RA2708 Tofacitinib 0.3
uM
 2
MMP-1
 1286.5 60
RA2708 2
MMP-1
 1784.0 36
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 260.0 44
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 556.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 90.0 46
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 112.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-1
 2236.0 74
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-1
 9565.0 52
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 352.0 51
RA2159 TNF-a 100
ng/mL
 2
MMP-1
 908.0 70
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 180.0 43
N2645 TNF-a 100
ng/mL
 2
MMP-1
 269.0 59
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-1
 28875.0 39
RA2708 TNF-a 100
ng/mL
 2
MMP-1
 23063.0 65
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 231.0 53
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 241.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 98.5 56
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 96.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 1496.5 80
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 5851.0 55
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-1
 1240.0 64
RA2159 IL-1 alpha 100
ng/mL
 2
MMP-1
 1646.0 73