Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 76.0 | 49 | |
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 568.0 | 49 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 66.0 | 76 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 59.5 | 56 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 201.0 | 49 | ||||
| N2586 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 156.0 | 57 | |
| N2759 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 560.0 | 61 | |
| RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 63.0 | 71 | |
| N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 66.0 | 73 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 65.0 | 68 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 141.5 | 58 | |
| N2759 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 200.0 | 59 | |
| RA1931 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 137.0 | 67 | |
| RA1931 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 133.0 | 51 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 148.0 | 77 | ||||
| RA1869 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 123.0 | 70 | |
| N2586 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 399.0 | 64 | |
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 62.0 | 64 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 528.5 | 82 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 308.0 | 73 | ||||
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 131.0 | 76 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 61.5 | 74 | |
| RA1869 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 91.0 | 67 | |
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 109.5 | 60 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 374.0 | 40 |