Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MIP-1B | 465.0 | 59 | |
| RA2708 | Tofacitinib | 0.3 | uM | 2 | MIP-1B | 67.0 | 63 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 118.0 | 57 | |
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MIP-1B | 1031.5 | 56 | |
| RA1931 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 54.5 | 44 | ||||
| N2645 | Tofacitinib | 0.3 | uM | 2 | MIP-1B | 48.0 | 66 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 64.5 | 64 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 144.0 | 57 | |
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 568.0 | 49 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MIP-1B | 60.0 | 57 | |
| RA1869 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 57.0 | 61 | ||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 63.5 | 46 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 66.0 | 51 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 2 | MIP-1B | 61.0 | 83 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 62.0 | 63 | ||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 62.5 | 70 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 55.0 | 57 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 113.5 | 78 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 144.0 | 58 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 141.5 | 58 | |
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 109.5 | 60 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 258.0 | 63 | |
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MIP-1B | 424.0 | 41 | |
| N2645 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 2 | MIP-1B | 101.5 | 58 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 2 | MIP-1B | 126.0 | 46 |