Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 4
b-NGF
 131.0 46
N2645 IKK16 2.0
uM
 4
b-NGF
 177.0 47
RA2708 5z-7-oxozeaenol 0.6
uM
 4
b-NGF
 41.0 39
RA2708 IKK16 2.0
uM
 4
b-NGF
 26.5 50
RA2159 Tofacitinib 0.3
uM
 4
b-NGF
 20.0 60
RA2159 4
b-NGF
 23.5 36
N2645 Tofacitinib 0.3
uM
 4
b-NGF
 226.0 43
N2645 4
b-NGF
 298.0 25
RA2708 Tofacitinib 0.3
uM
 4
b-NGF
 31.0 46
RA2708 4
b-NGF
 24.0 41
RA2159 4
b-NGF
 33.0 60
N2645 4
b-NGF
 236.5 44
RA2708 4
b-NGF
 40.5 58
RA2159 JNK-IN-8 3.0
uM
 4
b-NGF
 25.5 48
RA2159 PH-797804 0.6
uM
 4
b-NGF
 20.0 45
N2645 JNK-IN-8 3.0
uM
 4
b-NGF
 234.5 54
N2645 PH-797804 0.6
uM
 4
b-NGF
 260.0 34
RA2708 JNK-IN-8 3.0
uM
 4
b-NGF
 32.0 30
RA2708 PH-797804 0.6
uM
 4
b-NGF
 25.0 33
RA2159 Poly(I:C) 2
ug/mL
 4
b-NGF
 59.0 59
N2645 Poly(I:C) 2
ug/mL
 4
b-NGF
 321.0 47
RA2708 Poly(I:C) 2
ug/mL
 4
b-NGF
 78.0 47
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
b-NGF
 54.0 33
RA2159 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 4
b-NGF
 32.0 47
N2645 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
b-NGF
 368.0 39