Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 46.0 49
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 196.5 46
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 262.5 54
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 52.0 72
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 50.5 62
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 69.5 58
RA2159 IL-1 alpha 100
ng/mL
 4
b-NGF
 66.0 52
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 454.5 44
N2645 IL-1 alpha 100
ng/mL
 4
b-NGF
 475.5 42
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 99.0 49
RA2708 IL-1 alpha 100
ng/mL
 4
b-NGF
 83.5 48
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 35.0 67
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 29.5 64
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 131.0 49
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 162.0 52
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 35.5 58
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 33.0 43
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 44.5 52
RA2159 TNF-a 100
ng/mL
 4
b-NGF
 46.5 64
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 319.5 46
N2645 TNF-a 100
ng/mL
 4
b-NGF
 348.0 50
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 66.0 44
RA2708 TNF-a 100
ng/mL
 4
b-NGF
 63.0 42
RA2159 5z-7-oxozeaenol 0.6
uM
 4
b-NGF
 30.0 47
RA2159 IKK16 2.0
uM
 4
b-NGF
 20.0 45