Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 3
MCP3
 16.0 74
RA1931 3
MCP3
 13.0 67
N2586 Tofacitinib 0.3
uM
 3
MCP3
 19.5 76
N2586 3
MCP3
 21.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 18.0 83
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 19.0 75
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 19.0 108
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 19.0 101
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 16.0 94
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 30.5 78
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 16.5 76
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 28.0 85
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 32.0 99
RA1869 Poly(I:C) 2
ug/mL
 3
MCP3
 41.0 80
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 20.0 67
N2759 Poly(I:C) 2
ug/mL
 3
MCP3
 26.0 69
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 35.0 69
RA1931 Poly(I:C) 2
ug/mL
 3
MCP3
 57.0 57
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 73.0 66
N2586 Poly(I:C) 2
ug/mL
 3
MCP3
 60.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 18.0 102
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 33.0 102
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 22.5 86
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 19.5 98
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 23.0 93