Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 27.0 76
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 27.0 77
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 44.0 79
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 106.5 82
RA1869 IL-1 alpha 100
ng/mL
 3
MCP3
 24.5 92
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 123.0 85
N2759 IL-1 alpha 100
ng/mL
 3
MCP3
 144.0 71
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 217.0 50
RA1931 IL-1 alpha 100
ng/mL
 3
MCP3
 223.0 67
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 269.0 68
N2586 IL-1 alpha 100
ng/mL
 3
MCP3
 306.0 71
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 18.0 79
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 25.0 82
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 16.0 89
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 23.0 89
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 16.5 98
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 18.5 74
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 14.0 69
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 32.5 78
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 27.5 82
RA1869 TNF-a 100
ng/mL
 3
MCP3
 33.0 75
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 33.0 76
N2759 TNF-a 100
ng/mL
 3
MCP3
 25.0 65
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 27.0 77
RA1931 TNF-a 100
ng/mL
 3
MCP3
 28.0 64