Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MIF
 83.0 67
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MIF
 42.0 61
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MIF
 28.0 67
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MIF
 251.0 55
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MIF
 57.5 52
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIF
 26.0 57
RA1869 TNF-a 100
ng/mL
 1
MIF
 34.0 54
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIF
 26.0 43
N2759 TNF-a 100
ng/mL
 1
MIF
 23.0 45
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIF
 27.5 46
RA1931 TNF-a 100
ng/mL
 1
MIF
 21.5 48
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIF
 28.0 63
N2586 TNF-a 100
ng/mL
 1
MIF
 31.5 62
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 40.0 37
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 35.0 56
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 36.0 62
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 32.5 42
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 31.0 52
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 21.0 47
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 29.0 54
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 29.5 54
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 26.0 49
RA1869 IL-1 alpha 100
ng/mL
 1
MIF
 46.0 43
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIF
 31.0 56
N2759 IL-1 alpha 100
ng/mL
 1
MIF
 30.0 38